| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lmac_1241 | Lmac_2051 | Lmac_1241 | Lmac_2051 | Single strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Single-strand DNA-binding protein. | 0.664 |
| Lmac_1241 | topA | Lmac_1241 | Lmac_1059 | Single strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.956 |
| Lmac_2051 | Lmac_1241 | Lmac_2051 | Lmac_1241 | Single-strand DNA-binding protein. | Single strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.664 |
| Lmac_2051 | ssb | Lmac_2051 | Lmac_0830 | Single-strand DNA-binding protein. | Single-strand binding protein (SSB) (Helix-destabilizing protein). | 0.821 |
| Lmac_2051 | topA | Lmac_2051 | Lmac_1059 | Single-strand DNA-binding protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.956 |
| Lmac_2084 | korA | Lmac_2084 | Lmac_2458 | Potassium efflux system KefA. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.459 |
| Lmac_2084 | recA | Lmac_2084 | Lmac_1662 | Potassium efflux system KefA. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.894 |
| Lmac_2084 | recQ | Lmac_2084 | Lmac_0913 | Potassium efflux system KefA. | ATP-dependent DNA helicase. | 0.977 |
| Lmac_2084 | topA | Lmac_2084 | Lmac_1059 | Potassium efflux system KefA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.913 |
| Lmac_2137 | topA | Lmac_2137 | Lmac_1059 | Single strand DNA binding protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.956 |
| korA | Lmac_2084 | Lmac_2458 | Lmac_2084 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | Potassium efflux system KefA. | 0.459 |
| korA | leuS | Lmac_2458 | Lmac_1543 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.539 |
| korA | recA | Lmac_2458 | Lmac_1662 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.454 |
| korA | topA | Lmac_2458 | Lmac_1059 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.982 |
| leuS | korA | Lmac_1543 | Lmac_2458 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.539 |
| leuS | recA | Lmac_1543 | Lmac_1662 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.504 |
| leuS | rpoA | Lmac_1543 | Lmac_1238 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.603 |
| leuS | topA | Lmac_1543 | Lmac_1059 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.987 |
| recA | Lmac_2084 | Lmac_1662 | Lmac_2084 | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Potassium efflux system KefA. | 0.894 |
| recA | korA | Lmac_1662 | Lmac_2458 | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.454 |