| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lmac_1063 | Lmac_1064 | Lmac_1063 | Lmac_1064 | Putative aminoglycoside phosphotransferase. | Transmembrane protein. | 0.798 |
| Lmac_1063 | ltaE | Lmac_1063 | Lmac_1062 | Putative aminoglycoside phosphotransferase. | Low specificity L-threonine aldolase. | 0.793 |
| Lmac_1064 | Lmac_1063 | Lmac_1064 | Lmac_1063 | Transmembrane protein. | Putative aminoglycoside phosphotransferase. | 0.798 |
| Lmac_1064 | ltaE | Lmac_1064 | Lmac_1062 | Transmembrane protein. | Low specificity L-threonine aldolase. | 0.793 |
| Lmac_2148 | cysK | Lmac_2148 | Lmac_3088 | Polyketide synthase module. | Cystathionine beta synthase. | 0.570 |
| Lmac_2148 | gcvPB | Lmac_2148 | Lmac_3145 | Polyketide synthase module. | Putative glycine dehydrogenase [decarboxylating] subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.552 |
| Lmac_2148 | gcvT | Lmac_2148 | Lmac_3141 | Polyketide synthase module. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.789 |
| Lmac_2148 | glyA | Lmac_2148 | Lmac_0426 | Polyketide synthase module. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.801 |
| Lmac_2148 | ltaE | Lmac_2148 | Lmac_1062 | Polyketide synthase module. | Low specificity L-threonine aldolase. | 0.690 |
| Lmac_2148 | tdcB | Lmac_2148 | Lmac_0883 | Polyketide synthase module. | L-threonine dehydratase catabolic TdcB. | 0.617 |
| cysK | Lmac_2148 | Lmac_3088 | Lmac_2148 | Cystathionine beta synthase. | Polyketide synthase module. | 0.570 |
| cysK | glyA | Lmac_3088 | Lmac_0426 | Cystathionine beta synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.746 |
| cysK | ltaE | Lmac_3088 | Lmac_1062 | Cystathionine beta synthase. | Low specificity L-threonine aldolase. | 0.680 |
| cysK | tdcB | Lmac_3088 | Lmac_0883 | Cystathionine beta synthase. | L-threonine dehydratase catabolic TdcB. | 0.755 |
| gcsA | gcvPB | Lmac_3143 | Lmac_3145 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative glycine dehydrogenase [decarboxylating] subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.999 |
| gcsA | gcvT | Lmac_3143 | Lmac_3141 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcsA | glyA | Lmac_3143 | Lmac_0426 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.838 |
| gcsA | ltaE | Lmac_3143 | Lmac_1062 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Low specificity L-threonine aldolase. | 0.700 |
| gcvPB | Lmac_2148 | Lmac_3145 | Lmac_2148 | Putative glycine dehydrogenase [decarboxylating] subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | Polyketide synthase module. | 0.552 |
| gcvPB | gcsA | Lmac_3145 | Lmac_3143 | Putative glycine dehydrogenase [decarboxylating] subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |