STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_1128ATPase N2B (nucleotide (GTP) binding protein). (362 aa)    
Predicted Functional Partners:
Lmac_1129
Alpha/beta superfamily transporter hydrolase.
 
     0.821
sdhB
Succinate dehydrogenase iron-sulfur subunit.
 
     0.716
sdhA_2
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
    0.697
Lmac_1125
Outer membrane efflux protein.
       0.554
Lmac_1126
Membrane-fusion protein involved in transport; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.554
Lmac_1127
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.554
Lmac_1110
Succinate dehydrogenase cytochrome b556 subunit C.
 
   
 0.524
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.522
Lmac_1124
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
       0.468
Lmac_2765
Electron transferring flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.
 
     0.468
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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