Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gorGlutathione reductase. (449 aa)    
Predicted Functional Partners:
Lmac_1043
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 0.984
btuE
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.930
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
     
 0.905
Lmac_1090
Gamma-glutamyltranspeptidase.
     
 0.895
sucA
2-oxoglutarate dehydrogenase E1.
  
 0.879
odpB
Pyruvate dehydrogenase E1 subunit beta.
 
 0.879
Lmac_1789
Glutathione S-transferase; Belongs to the GST superfamily.
     
 0.877
Lmac_1367
Transferase.
       0.872
aceF
Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.841
sucB
Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.829
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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