Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phaB_1Pteridine reductase. (250 aa)    
Predicted Functional Partners:
pksJ
Polyketide synthase, type I.
  
 0.957
Lmac_1430
Non-ribosomal peptide synthetase/polyketide synthetase.
  
 0.867
folA
Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.860
Lmac_0390
Phenylalanine-4-hydroxylase.
     
  0.858
Lmac_2148
Polyketide synthase module.
  
 0.798
Lmac_1481
6-pyruvoyl tetrahydropterin synthase.
    
  0.789
priA
Primosomal protein N' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.783
Lmac_1480
Hypothetical protein.
       0.746
Lmac_0104
Oxidoreductase dehydrogenase, short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.722
Lmac_2640
Short chain dehydrogenase/reductase family oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
  0.717
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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