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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Lmac_14893-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)    
Predicted Functional Partners:
Lmac_0910
Enoyl-CoA hydratase/carnithine racemase.
 
 0.994
Lmac_1488
Methylmalonate-semialdehyde dehydrogenase.
 
 
 0.987
acsB
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.982
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
 0.872
Lmac_3178
Branched-chain alpha-keto acid dehydrogenase subunit E2.
     
 0.863
ubiX_2
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
       0.773
Lmac_0960
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
  0.770
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
  0.770
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.705
Lmac_1189
Acetyl/propionyl-CoA carboxylase, beta subunit.
 
 
  0.687
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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