Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lmac_1521Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (284 aa)    
Predicted Functional Partners:
pilC
Pilus assembly protein PilC.
 
  
 0.989
pilB
Pilus assembly protein PilB.
 
 
 0.988
lspF
Type II secretory pathway protein LspF.
 
  
 0.923
lspE
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 
 0.913
Lmac_0900
DNA uptake/competence protein ComA.
 
  
 0.861
yggR_1
Transporter.
 
   
 0.802
pilM
Tfp pilus assembly protein, ATPase PilM.
 
  
 0.799
smf
Protein smf.
  
  
 0.792
yggR_2
Transporter.
 
   
 0.781
Lmac_1941
DotB.
 
   
 0.755
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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