Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_1558Hypothetical protein; Alpha-2-macroglobulin family N-terminal region. (1919 aa)    
Predicted Functional Partners:
pbpC
Penicillin binding protein 1C.
   
 0.977
nrdR
NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.701
Lmac_0023
Secreted protein.
  
     0.491
Lmac_2230
Sensor protein RstB.
  
     0.472
Lmac_1869
Hypothetical protein.
  
    0.464
iraA
Small-molecule methyltransferase IraA.
  
     0.458
pilZ
Type IV pilus assembly PilZ.
 
     0.411
Lmac_0302
Hypothetical protein.
  
     0.409
Lmac_1506
Hypothetical protein.
  
     0.409
chiA1
Chitinase A1 precursor.
  
     0.405
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
Server load: low (16%) [HD]