Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lmac_1649Aldo/keto reductase. (328 aa)    
Predicted Functional Partners:
Lmac_2714
D-xylose reductase III.
 
 0.840
Lmac_1650
DNA topoisomerase IV subunit B.
       0.762
hdaH
Histone deacetylase-like amidohydrolase.
   
  0.739
Lmac_0449
Oxidoreductase.
  
 
 0.540
pksJ
Polyketide synthase, type I.
   
 0.517
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
  0.438
yjeA
Endo-1,4-beta-xylanase.
    
  0.414
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.408
kdgK
2-dehydro-3-deoxygluconokinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.407
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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