Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilOTfp pilus assembly protein PilO. (200 aa)    
Predicted Functional Partners:
pilN
Tfp pilus assembly protein PilN.
 
 
 0.999
pilM
Tfp pilus assembly protein, ATPase PilM.
 
 
 0.993
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
 
 0.985
Lmac_1775
Type IV pilus biogenesis protein PilP.
  
  
 0.983
pilE
type-IV pilin.
 
  
 0.746
rhsA
Putative deoxyribonuclease RhsA.
   
   0.692
aroK_2
Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.677
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
       0.677
pilC
Pilus assembly protein PilC.
 
 
 
 0.643
pilF
Fimbrial biogenesis and twitching motility protein PilF.
  
   
 0.642
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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