Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lmac_1825Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (362 aa)    
Predicted Functional Partners:
Lmac_1043
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 
 0.983
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.946
pdhA
Pyruvate dehydrogenase e1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.937
Lmac_0768
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.910
Lmac_2148
Polyketide synthase module.
   
 0.907
odpB
Pyruvate dehydrogenase E1 subunit beta.
  
 
 0.904
ala_1
D-alanine-aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.895
Lmac_2636
Glutamate synthase; Belongs to the glutamate synthase family.
  
 0.881
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.851
pksJ
Polyketide synthase, type I.
  
 
 0.834
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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