STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (342 aa)    
Predicted Functional Partners:
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
   
 0.963
Lmac_1963
Mevalonate diphosphate decarboxylase.
 
  
 0.913
Lmac_1962
Putative mevalonate kinase.
 
  
 0.876
Lmac_1973
Hypothetical protein.
    
 0.864
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.798
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.771
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.688
ispB
Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family.
  
 
 0.658
Lmac_1043
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
     
 0.652
Lmac_0700
Cytokinin oxidase.
  
 0.633
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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