Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (342 aa)    
Predicted Functional Partners:
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
   
 0.975
Lmac_1963
Mevalonate diphosphate decarboxylase.
 
  
 0.966
Lmac_1973
Hypothetical protein.
    
 0.909
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.884
Lmac_1962
Putative mevalonate kinase.
 
  
 0.869
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.780
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.706
Lmac_1969
ABC transporter ATP binding protein.
       0.689
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.670
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 0.650
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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