STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_2008GTP cyclohydrolase II. (423 aa)    
Predicted Functional Partners:
Lmac_2009
Putative biotin synthetase like protein.
     0.995
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.960
ribE
Riboflavin synthase alpha chain.
  
 0.905
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
     0.896
Lmac_3099
6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.
  
 
 0.866
Lmac_0856
Sensory box histidine kinase/response regulator.
    
  0.862
Lmac_3100
6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.
  
 
 0.798
Lmac_0823
Sensory box sensor histidine kinase/response regulator.
    
 0.760
Lmac_1280
Sensory histidine-kinase / response regulator.
    
 0.760
Lmac_1292
Sensory box histidine kinase/response regulator.
    
 0.760
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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