Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ylpALipoprotein YlpA precursor. (250 aa)    
Predicted Functional Partners:
Lmac_2302
Sensor histidine kinase.
 
     0.840
Lmac_2287
Putative conjugative transfer protein TraB.
 
     0.783
Lmac_2281
Putative conjugative transfer protein TrbC.
 
     0.782
Lmac_2280
Conjugal transfer mating pair stabilization protein TraN.
 
     0.770
Lmac_2297
Hypothetical protein.
       0.758
parB_3
Putative chromosome-partitioning protein ParB.
  
     0.737
Lmac_2277
Putative conjugative transfer protein TraH.
 
     0.735
Lmac_2279
Putative conjugative transfer protein TraF.
 
     0.723
csrA-3
Global regulator (carbon storage regulator); A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
       0.714
Lmac_2300
Alpha/beta hydrolase family protein.
 
     0.703
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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