STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_2462Cytosolic IMP-GMP specific 5'-nucleotidase. (460 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
    0.658
Lmac_2436
PAS fold protein.
    
 0.655
Lmac_0823
Sensory box sensor histidine kinase/response regulator.
   
  0.596
Lmac_1280
Sensory histidine-kinase / response regulator.
   
  0.596
Lmac_1292
Sensory box histidine kinase/response regulator.
   
  0.596
Lmac_1811
Sensory box sensor histidine kinase/response regulator.
   
  0.596
Lmac_1813
Sensory histidine-kinase / response regulator.
   
  0.596
Lmac_2788
Sensory histidine-kinase / response regulator.
   
  0.596
Lmac_0400
Regulator of chromosome condensation (RCC1) repeat protein.
  
 
  0.568
Lmac_0117
GGDEF domain-containing sensory box protein.
     
  0.566
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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