| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | pabB | Lmac_2599 | Lmac_3174 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase, component I. | 0.957 |
| aroC | pheA | Lmac_2599 | Lmac_0342 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Prephenate dehydratase. | 0.990 |
| aroC | trpA | Lmac_2599 | Lmac_0742 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.734 |
| aroC | trpB | Lmac_2599 | Lmac_0743 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.514 |
| aroC | trpC | Lmac_2599 | Lmac_2473 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.582 |
| aroC | trpD | Lmac_2599 | Lmac_2474 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.790 |
| aroC | trpE | Lmac_2599 | Lmac_2228 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase. | 0.942 |
| aroC | trpF | Lmac_2599 | Lmac_0744 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.508 |
| aroC | trpG | Lmac_2599 | Lmac_2475 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component II. | 0.937 |
| aroC | ubiC | Lmac_2599 | Lmac_0486 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.858 |
| pabB | aroC | Lmac_3174 | Lmac_2599 | Para-aminobenzoate synthase, component I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.957 |
| pabB | pheA | Lmac_3174 | Lmac_0342 | Para-aminobenzoate synthase, component I. | Prephenate dehydratase. | 0.892 |
| pabB | trpA | Lmac_3174 | Lmac_0742 | Para-aminobenzoate synthase, component I. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.959 |
| pabB | trpB | Lmac_3174 | Lmac_0743 | Para-aminobenzoate synthase, component I. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.964 |
| pabB | trpC | Lmac_3174 | Lmac_2473 | Para-aminobenzoate synthase, component I. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.997 |
| pabB | trpD | Lmac_3174 | Lmac_2474 | Para-aminobenzoate synthase, component I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.997 |
| pabB | trpE | Lmac_3174 | Lmac_2228 | Para-aminobenzoate synthase, component I. | Anthranilate synthase. | 0.988 |
| pabB | trpF | Lmac_3174 | Lmac_0744 | Para-aminobenzoate synthase, component I. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.947 |
| pabB | trpG | Lmac_3174 | Lmac_2475 | Para-aminobenzoate synthase, component I. | Anthranilate synthase component II. | 0.999 |
| pabB | ubiC | Lmac_3174 | Lmac_0486 | Para-aminobenzoate synthase, component I. | 4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.474 |
