| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lmac_2148 | cfa_2 | Lmac_2148 | Lmac_3052 | Polyketide synthase module. | Cyclopropane fatty acyl phospholipid synthase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. | 0.620 |
| Lmac_2148 | glyA | Lmac_2148 | Lmac_0426 | Polyketide synthase module. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.801 |
| Lmac_2148 | mnmC | Lmac_2148 | Lmac_0961 | Polyketide synthase module. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.551 |
| Lmac_2148 | petC_2 | Lmac_2148 | Lmac_2446 | Polyketide synthase module. | Cytochrome b6-f complex iron-sulfur subunit. | 0.963 |
| Lmac_2148 | pksJ | Lmac_2148 | Lmac_2149 | Polyketide synthase module. | Polyketide synthase, type I. | 0.999 |
| Lmac_2148 | ubiG_2 | Lmac_2148 | Lmac_2486 | Polyketide synthase module. | 3-demethylubiquinone-9 3-methyltransferase. | 0.653 |
| Lmac_2148 | ubiH_1 | Lmac_2148 | Lmac_2721 | Polyketide synthase module. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.788 |
| Lmac_2148 | ubiH_2 | Lmac_2148 | Lmac_2722 | Polyketide synthase module. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.814 |
| cfa_2 | Lmac_2148 | Lmac_3052 | Lmac_2148 | Cyclopropane fatty acyl phospholipid synthase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. | Polyketide synthase module. | 0.620 |
| cfa_2 | petC_2 | Lmac_3052 | Lmac_2446 | Cyclopropane fatty acyl phospholipid synthase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. | Cytochrome b6-f complex iron-sulfur subunit. | 0.415 |
| cfa_2 | pksJ | Lmac_3052 | Lmac_2149 | Cyclopropane fatty acyl phospholipid synthase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. | Polyketide synthase, type I. | 0.490 |
| cfa_2 | ubiG_2 | Lmac_3052 | Lmac_2486 | Cyclopropane fatty acyl phospholipid synthase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. | 3-demethylubiquinone-9 3-methyltransferase. | 0.510 |
| coq7 | ubiG_2 | Lmac_2921 | Lmac_2486 | Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 3-demethylubiquinone-9 3-methyltransferase. | 0.599 |
| coq7 | ubiH_1 | Lmac_2921 | Lmac_2721 | Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.549 |
| coq7 | ubiH_2 | Lmac_2921 | Lmac_2722 | Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.549 |
| glyA | Lmac_2148 | Lmac_0426 | Lmac_2148 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Polyketide synthase module. | 0.801 |
| glyA | mnmC | Lmac_0426 | Lmac_0961 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.576 |
| glyA | petC_2 | Lmac_0426 | Lmac_2446 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cytochrome b6-f complex iron-sulfur subunit. | 0.552 |
| glyA | pksJ | Lmac_0426 | Lmac_2149 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Polyketide synthase, type I. | 0.825 |
| glyA | ubiG_2 | Lmac_0426 | Lmac_2486 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 3-demethylubiquinone-9 3-methyltransferase. | 0.500 |