STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrE_2Orotate phosphoribosyltransferase. (203 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.893
pyrF
Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.885
carB_1
Carbamoyl-phosphate synthase large subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.862
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.832
hydG-2
Hydrogenase/sulfur reductase subunit gamma.
  
 
 0.826
Lmac_3000
CDP-6-deoxy-delta-3,4-glucoseen reductase.
  
 
 0.826
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.820
Lmac_2521
Transmembrane protein.
 
     0.801
carB_2
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
 
 0.781
carA
Carbamoyl phosphate synthase, small subunit; Belongs to the CarA family.
  
  
 0.759
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.