metK_2 protein (Legionella maceachernii) - STRING interaction network

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metK_2

S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (382 aa)

Predicted Functional Partners:

sahH

0.858

guaA

0.720

mscL

0.712

Lmac_3099

0.687

Lmac_3100

0.685

capI

0.645

galE

0.645

Lmac_1677

0.645

Lmac_2449

0.645

rfbG

0.645

Your Current Organism:

Legionella maceachernii

NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lmac_1677	metK_2	Lmac_1677	Lmac_2563	NAD-dependent epimerase/dehydratase.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.645
Lmac_2449	metK_2	Lmac_2449	Lmac_2563	NAD-dependent epimerase/dehydratase.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.645
Lmac_3099	Lmac_3100	Lmac_3099	Lmac_3100	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.858
Lmac_3099	metK_2	Lmac_3099	Lmac_2563	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.687
Lmac_3099	mscL	Lmac_3099	Lmac_1666	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	Mechanosensitive ion channel MscS; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	0.797
Lmac_3100	Lmac_3099	Lmac_3100	Lmac_3099	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.858
Lmac_3100	metK_2	Lmac_3100	Lmac_2563	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.685
Lmac_3100	mscL	Lmac_3100	Lmac_1666	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	Mechanosensitive ion channel MscS; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	0.797
capI	metK_2	Lmac_0318	Lmac_2563	Protein capI.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.645
galE	metK_2	Lmac_0662	Lmac_2563	UDP-glucose 4-epimerase.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.645
guaA	metK_2	Lmac_0556	Lmac_2563	GMP synthase; Catalyzes the synthesis of GMP from XMP.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.720
metK_2	Lmac_1677	Lmac_2563	Lmac_1677	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	NAD-dependent epimerase/dehydratase.	0.645
metK_2	Lmac_2449	Lmac_2563	Lmac_2449	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	NAD-dependent epimerase/dehydratase.	0.645
metK_2	Lmac_3099	Lmac_2563	Lmac_3099	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.687
metK_2	Lmac_3100	Lmac_2563	Lmac_3100	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.685
metK_2	capI	Lmac_2563	Lmac_0318	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	Protein capI.	0.645
metK_2	galE	Lmac_2563	Lmac_0662	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	UDP-glucose 4-epimerase.	0.645
metK_2	guaA	Lmac_2563	Lmac_0556	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.720
metK_2	mscL	Lmac_2563	Lmac_1666	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	Mechanosensitive ion channel MscS; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	0.712
metK_2	rfbG	Lmac_2563	Lmac_3007	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	CDP-glucose 4,6-dehydratase.	0.645

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