Lmac_2576 protein (Legionella maceachernii) - STRING interaction network

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Score

Lmac_2576

Putative stress-induced protein. (288 aa)

Predicted Functional Partners:

gmk

0.952

rpoZ

0.704

spoT

0.599

Lmac_2580

0.599

rph

0.491

Your Current Organism:

Legionella maceachernii

NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lmac_2576	Lmac_2580	Lmac_2576	Lmac_2580	Putative stress-induced protein.	Endoribonuclease L-PSP.	0.599
Lmac_2576	gmk	Lmac_2576	Lmac_2577	Putative stress-induced protein.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.952
Lmac_2576	rph	Lmac_2576	Lmac_2575	Putative stress-induced protein.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.491
Lmac_2576	rpoZ	Lmac_2576	Lmac_2578	Putative stress-induced protein.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.704
Lmac_2576	spoT	Lmac_2576	Lmac_2579	Putative stress-induced protein.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.599
Lmac_2580	Lmac_2576	Lmac_2580	Lmac_2576	Endoribonuclease L-PSP.	Putative stress-induced protein.	0.599
Lmac_2580	gmk	Lmac_2580	Lmac_2577	Endoribonuclease L-PSP.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.620
Lmac_2580	rph	Lmac_2580	Lmac_2575	Endoribonuclease L-PSP.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.594
Lmac_2580	rpoZ	Lmac_2580	Lmac_2578	Endoribonuclease L-PSP.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.663
Lmac_2580	spoT	Lmac_2580	Lmac_2579	Endoribonuclease L-PSP.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.872
gmk	Lmac_2576	Lmac_2577	Lmac_2576	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Putative stress-induced protein.	0.952
gmk	Lmac_2580	Lmac_2577	Lmac_2580	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Endoribonuclease L-PSP.	0.620
gmk	rph	Lmac_2577	Lmac_2575	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.503
gmk	rpoZ	Lmac_2577	Lmac_2578	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.915
gmk	spoT	Lmac_2577	Lmac_2579	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.946
rph	Lmac_2576	Lmac_2575	Lmac_2576	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Putative stress-induced protein.	0.491
rph	Lmac_2580	Lmac_2575	Lmac_2580	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Endoribonuclease L-PSP.	0.594
rph	gmk	Lmac_2575	Lmac_2577	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.503
rph	rpoZ	Lmac_2575	Lmac_2578	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.554
rph	spoT	Lmac_2575	Lmac_2579	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.437

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