Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_2614Protein IcmE (DotG). (535 aa)    
Predicted Functional Partners:
pipB2_2
Secreted effector protein pipB2.
  
     0.767
pipB2_1
Secreted effector protein pipB2.
  
     0.747
Lmac_3048
SET domain protein.
  
     0.662
Lmac_0633
RasGEF domain protein.
  
  
  0.618
rhsA
Putative deoxyribonuclease RhsA.
 
     0.616
Lmac_2173
Phosphoprotein phosphatase.
  
     0.615
Lmac_0290
Eukaryotic huntingtin interacting protein B.
  
     0.608
Lmac_1639
Ankyrin repeat protein.
  
     0.597
Lmac_2906
DNA-binding transcriptional dual regulator Crp.
  
     0.595
Lmac_2775
HEAT repeat protein.
  
     0.587
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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