Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_2636Glutamate synthase; Belongs to the glutamate synthase family. (507 aa)    
Predicted Functional Partners:
fadH
2,4-dienoyl-CoA reductase FadH1.
 
 0.997
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.946
Lmac_1825
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.881
pksJ
Polyketide synthase, type I.
  
 
 0.816
Lmac_1430
Non-ribosomal peptide synthetase/polyketide synthetase.
     
 0.815
Lmac_2148
Polyketide synthase module.
   
 
 0.814
Lmac_0768
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.798
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.788
Lmac_2711
Polyketide synthase module.
     
 0.776
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.702
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
Server load: low (24%) [HD]