Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (360 aa)    
Predicted Functional Partners:
fcl
Bifunctional GDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.982
cpsB_2
Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.927
cpsB_1
Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.922
Lmac_3004
Glycosyltransferase.
       0.796
Lmac_0587
Capsular polysaccharide biosynthesis protein CapD and UDP-glucose 4-epimerase.
  
  
 0.767
ugd
UDP-glucose 6-dehydrogenase.
    
 0.714
rfbG
CDP-glucose 4,6-dehydratase.
  
 0.686
gca
GDP-mannose 4,6-dehydratase.
  
  
 
0.622
algC
Phosphomannomutase.
  
 
 0.586
rfbF_1
Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).
    
  0.574
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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