Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lhgOL-2-hydroxyglutarate oxidase LhgO. (398 aa)    
Predicted Functional Partners:
coxB
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
 
 0.905
Lmac_3020
NAD dependent epimerase/dehydratase family protein.
 
     0.798
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
       0.747
rfbF_1
Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).
       0.743
yvfE_1
Cell wall biosynthesis regulatory pyridoxal phosphate-dependent protein; Belongs to the DegT/DnrJ/EryC1 family.
       0.741
Lmac_3016
Hypothetical protein.
 
     0.709
petB
Ubiquinol-cytochrome c reductase, cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 
 0.680
hddA
D-glycero-alpha-D-manno-heptose 7-phosphate kinase.
       0.675
Lmac_3015
Hypothetical protein.
       0.672
coxC
Cytochrome c oxidase, subunit III.
    
   0.657
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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