Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
budBAcetolactate synthase; Belongs to the TPP enzyme family. (575 aa)    
Predicted Functional Partners:
tdcB
L-threonine dehydratase catabolic TdcB.
 
 0.910
dlpA_1
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein).
 
 0.873
Lmac_2459
2-oxoglutarate ferredoxin oxidoreductase beta subunit.
    
 0.811
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.803
Lmac_0960
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.795
Lmac_1923
4-hydroxy-2-oxovalerate aldolase.
 
 
 0.767
pksJ
Polyketide synthase, type I.
  
 
 0.734
Lmac_1043
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.711
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.686
mao2
Malate oxidoreductase.
   
 0.681
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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