node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMB85802.1 | AMB87969.1 | AWM79_11010 | AWM79_22895 | Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
AMB85802.1 | recA | AWM79_11010 | AWM79_11015 | Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.753 |
AMB85802.1 | recX | AWM79_11010 | AWM79_11020 | Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Recombinase RecX; Modulates RecA activity; Belongs to the RecX family. | 0.687 |
AMB85810.1 | murG | AWM79_11050 | AWM79_16780 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.704 |
AMB85810.1 | recO | AWM79_11050 | AWM79_03760 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.528 |
AMB85810.1 | recX | AWM79_11050 | AWM79_11020 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Recombinase RecX; Modulates RecA activity; Belongs to the RecX family. | 0.698 |
AMB87969.1 | AMB85802.1 | AWM79_22895 | AWM79_11010 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | 0.479 |
AMB87969.1 | radA | AWM79_22895 | AWM79_22500 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.516 |
AMB87969.1 | recA | AWM79_22895 | AWM79_11015 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.598 |
AMB87969.1 | recG | AWM79_22895 | AWM79_02635 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.525 |
AMB87969.1 | recX | AWM79_22895 | AWM79_11020 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecX; Modulates RecA activity; Belongs to the RecX family. | 0.640 |
AMB87969.1 | ruvA | AWM79_22895 | AWM79_12020 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.567 |
AMB87969.1 | ruvC | AWM79_22895 | AWM79_12015 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.514 |
murG | AMB85810.1 | AWM79_16780 | AWM79_11050 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 0.704 |
murG | recX | AWM79_16780 | AWM79_11020 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Recombinase RecX; Modulates RecA activity; Belongs to the RecX family. | 0.737 |
radA | AMB87969.1 | AWM79_22500 | AWM79_22895 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.516 |
radA | recA | AWM79_22500 | AWM79_11015 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.896 |
radA | recG | AWM79_22500 | AWM79_02635 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.490 |
radA | recX | AWM79_22500 | AWM79_11020 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Recombinase RecX; Modulates RecA activity; Belongs to the RecX family. | 0.898 |
radA | ruvA | AWM79_22500 | AWM79_12020 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.406 |