| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMB84897.1 | AMB84990.1 | AWM79_06070 | AWM79_06565 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.564 |
| AMB84897.1 | AMB84994.1 | AWM79_06070 | AWM79_06585 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| AMB84897.1 | AMB87322.1 | AWM79_06070 | AWM79_19290 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| AMB84897.1 | AMB87323.1 | AWM79_06070 | AWM79_19300 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| AMB84897.1 | AMB87324.1 | AWM79_06070 | AWM79_19305 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.435 |
| AMB84897.1 | AMB87325.1 | AWM79_06070 | AWM79_19310 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| AMB84897.1 | AMB87327.1 | AWM79_06070 | AWM79_19320 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6A reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |
| AMB84897.1 | AMB88234.1 | AWM79_06070 | AWM79_06065 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
| AMB84897.1 | AMB88354.1 | AWM79_06070 | AWM79_19295 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.926 |
| AMB84897.1 | cbiD | AWM79_06070 | AWM79_19315 | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-5B (C(1))-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.984 |
| AMB84990.1 | AMB84897.1 | AWM79_06565 | AWM79_06070 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.564 |
| AMB84990.1 | AMB84994.1 | AWM79_06565 | AWM79_06585 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
| AMB84990.1 | AMB87322.1 | AWM79_06565 | AWM79_19290 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.878 |
| AMB84990.1 | AMB87323.1 | AWM79_06565 | AWM79_19300 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.857 |
| AMB84990.1 | AMB87325.1 | AWM79_06565 | AWM79_19310 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| AMB84990.1 | AMB87327.1 | AWM79_06565 | AWM79_19320 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6A reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.842 |
| AMB84990.1 | AMB88234.1 | AWM79_06565 | AWM79_06065 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.700 |
| AMB84990.1 | AMB88354.1 | AWM79_06565 | AWM79_19295 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.818 |
| AMB84990.1 | cbiD | AWM79_06565 | AWM79_19315 | Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-5B (C(1))-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.736 |
| AMB84994.1 | AMB84897.1 | AWM79_06585 | AWM79_06070 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |