node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDU85961.1 | SDV06295.1 | SAMN05216202_0701 | SAMN05216202_4071 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.925 |
SDU85961.1 | dnaA | SAMN05216202_0701 | SAMN05216202_4617 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.837 |
SDU85961.1 | dnaX | SAMN05216202_0701 | SAMN05216202_2962 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.417 |
SDU87826.1 | SDU87833.1 | SAMN05216202_0971 | SAMN05216202_0972 | Hypothetical protein. | Protein of unknown function. | 0.771 |
SDU87826.1 | SDV06295.1 | SAMN05216202_0971 | SAMN05216202_4071 | Hypothetical protein. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.936 |
SDU87833.1 | SDU87826.1 | SAMN05216202_0972 | SAMN05216202_0971 | Protein of unknown function. | Hypothetical protein. | 0.771 |
SDU87833.1 | SDV06295.1 | SAMN05216202_0972 | SAMN05216202_4071 | Protein of unknown function. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.936 |
SDV06295.1 | SDU85961.1 | SAMN05216202_4071 | SAMN05216202_0701 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | 0.925 |
SDV06295.1 | SDU87826.1 | SAMN05216202_4071 | SAMN05216202_0971 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein. | 0.936 |
SDV06295.1 | SDU87833.1 | SAMN05216202_4071 | SAMN05216202_0972 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Protein of unknown function. | 0.936 |
SDV06295.1 | SDV07790.1 | SAMN05216202_4071 | SAMN05216202_4418 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase, catalytic core. | 0.969 |
SDV06295.1 | SDV11595.1 | SAMN05216202_4071 | SAMN05216202_5306 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.840 |
SDV06295.1 | dnaA | SAMN05216202_4071 | SAMN05216202_4617 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.961 |
SDV06295.1 | dnaG | SAMN05216202_4071 | SAMN05216202_5195 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.985 |
SDV06295.1 | dnaX | SAMN05216202_4071 | SAMN05216202_2962 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.950 |
SDV06295.1 | rpoA | SAMN05216202_4071 | SAMN05216202_5300 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.804 |
SDV06295.1 | tuf | SAMN05216202_4071 | SAMN05216202_5272 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.889 |
SDV07790.1 | SDV06295.1 | SAMN05216202_4418 | SAMN05216202_4071 | DNA primase, catalytic core. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.969 |
SDV07790.1 | dnaA | SAMN05216202_4418 | SAMN05216202_4617 | DNA primase, catalytic core. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.404 |
SDV07790.1 | dnaX | SAMN05216202_4418 | SAMN05216202_2962 | DNA primase, catalytic core. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.489 |