node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEG18_03845 | CEG18_17840 | GCA_000807755_05032 | GCA_000807755_00984 | Unannotated protein. | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.884 |
CEG18_03845 | CEG18_18525 | GCA_000807755_05032 | GCA_000807755_03888 | Unannotated protein. | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | 0.541 |
CEG18_03845 | glyA | GCA_000807755_05032 | GCA_000807755_02241 | Unannotated protein. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.535 |
CEG18_03845 | glyA-2 | GCA_000807755_05032 | GCA_000807755_04406 | Unannotated protein. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.535 |
CEG18_10395 | CEG18_18525 | GCA_000807755_00094 | GCA_000807755_03888 | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | 0.764 |
CEG18_10395 | glyA | GCA_000807755_00094 | GCA_000807755_02241 | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.830 |
CEG18_10395 | glyA-2 | GCA_000807755_00094 | GCA_000807755_04406 | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.830 |
CEG18_10395 | metG | GCA_000807755_00094 | GCA_000807755_03665 | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Unannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.856 |
CEG18_17840 | CEG18_03845 | GCA_000807755_00984 | GCA_000807755_05032 | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Unannotated protein. | 0.884 |
CEG18_17840 | CEG18_18525 | GCA_000807755_00984 | GCA_000807755_03888 | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | 0.750 |
CEG18_17840 | metG | GCA_000807755_00984 | GCA_000807755_03665 | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Unannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.540 |
CEG18_18510 | CEG18_18520 | GCA_000807755_03885 | GCA_000807755_03887 | Unannotated protein. | Unannotated protein. | 0.682 |
CEG18_18510 | CEG18_18525 | GCA_000807755_03885 | GCA_000807755_03888 | Unannotated protein. | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | 0.531 |
CEG18_18510 | sbcD | GCA_000807755_03885 | GCA_000807755_03886 | Unannotated protein. | Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.650 |
CEG18_18520 | CEG18_18510 | GCA_000807755_03887 | GCA_000807755_03885 | Unannotated protein. | Unannotated protein. | 0.682 |
CEG18_18520 | CEG18_18525 | GCA_000807755_03887 | GCA_000807755_03888 | Unannotated protein. | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | 0.773 |
CEG18_18520 | CEG18_18535 | GCA_000807755_03887 | GCA_000807755_03889 | Unannotated protein. | Unannotated protein; Belongs to the Dps family. | 0.495 |
CEG18_18520 | sbcD | GCA_000807755_03887 | GCA_000807755_03886 | Unannotated protein. | Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.999 |
CEG18_18525 | CEG18_03845 | GCA_000807755_03888 | GCA_000807755_05032 | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | Unannotated protein. | 0.541 |
CEG18_18525 | CEG18_10395 | GCA_000807755_03888 | GCA_000807755_00094 | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring. | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.764 |