STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL37281.1S-adenosyl-L-homocysteine hydrolase. (375 aa)    
Predicted Functional Partners:
EFL42248.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.965
EFL40981.1
Cystathionine beta-synthase.
 
 0.953
EFL38945.1
Methionine synthase, vitamin-B12 independent.
  
 
 0.921
EFL41033.1
Adenosylhomocysteinase.
  
  
 
0.894
EFL39098.1
Homoserine dehydrogenase.
  
 
  0.881
EFL37280.1
NUDIX family hydrolase.
       0.878
EFL39480.1
Cystathionine gamma-synthase.
  
 0.878
EFL40417.1
Cys/Met metabolism PLP-dependent enzyme.
  
 0.878
EFL42770.1
Pyridoxal-phosphate dependent enzyme.
  
 0.874
EFL37282.1
NAD dependent epimerase/dehydratase.
 
     0.872
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.