Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL37283.1Conserved hypothetical protein. (107 aa)    
Predicted Functional Partners:
EFL42248.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.777
EFL40981.1
Cystathionine beta-synthase.
    
  0.674
EFL37281.1
S-adenosyl-L-homocysteine hydrolase.
    
  0.657
EFL37282.1
NAD dependent epimerase/dehydratase.
       0.627
EFL42069.1
precorrin-3B C(17)-methyltransferase.
  
    0.603
EFL37280.1
NUDIX family hydrolase.
       0.581
EFL37279.1
3-deoxy-manno-octulosonate cytidylyltransferase.
       0.535
EFL38760.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
   
 
 0.500
EFL38759.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
   
 
 0.476
EFL39098.1
Homoserine dehydrogenase.
    
 0.458
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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