Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL37423.1Phosphotransferase enzyme family protein. (282 aa)    
Predicted Functional Partners:
EFL42248.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.777
EFL40981.1
Cystathionine beta-synthase.
    
  0.674
EFL42069.1
precorrin-3B C(17)-methyltransferase.
  
    0.603
EFL43321.1
Regulatory protein.
  
     0.588
vgb
Virginiamycin B lyase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.
  
     0.570
EFL38584.1
Secreted hydrolase.
  
     0.504
EFL38760.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
   
 
 0.500
EFL37375.1
M23 peptidase domain-containing protein.
  
     0.482
EFL38759.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
   
 
 0.476
EFL42538.1
6-phosphogluconate dehydrogenase, NAD-binding.
  
     0.466
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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