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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)    
Predicted Functional Partners:
EFL39932.1
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.999
EFL39938.1
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase.
 0.999
EFL42362.1
uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.997
EFL41096.1
uroporphyrinogen-III synthase.
  
 0.992
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 0.974
hemL
Glutamate-1-semialdehyde-2,1-aminomutase.
 
  
 0.928
hemC-2
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 
0.913
EFL39940.1
glutamyl-tRNA reductase (GluTR).
  
 0.906
EFL38569.1
Glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.845
EFL37625.1
Secreted protein.
       0.787
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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