STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL37735.1Pyruvate dehydrogenase complex, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (496 aa)    
Predicted Functional Partners:
EFL39170.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
 0.999
EFL40309.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
 0.999
EFL40307.1
Pyruvate dehydrogenase E2.
 
 0.998
EFL40320.1
Pyruvate dehydrogenase E2.
 
 0.998
EFL41746.1
Dihydrolipoyl dehydrogenase.
 
 0.997
EFL41745.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
 
 0.995
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.990
EFL39502.1
Dihydrolipoyl dehydrogenase.
 
 0.988
EFL42981.1
Mercuric reductase/transcriptional regulator, fusion.
 
 0.977
EFL37751.1
Secreted oxidase.
  
 0.967
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.