Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL38068.1Conserved hypothetical protein. (190 aa)    
Predicted Functional Partners:
EFL38760.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
  
 0.940
EFL38759.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
  
 0.891
EFL42695.1
Hypothetical protein.
  
 0.724
EFL38067.1
Lipoate-protein ligase.
       0.720
EFL42149.1
ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.708
EFL37442.1
PAS/PAC sensor hybrid histidine kinase.
   
 0.706
EFL37443.1
PAS/PAC sensor hybrid histidine kinase.
   
 0.706
EFL39950.1
Acetoin utilization protein AcuC.
    
 0.665
EFL38691.1
DNA gyrase subunit B.
   
 
 0.663
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.663
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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