STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL38183.1hydroxymethylglutaryl-CoA synthase. (391 aa)    
Predicted Functional Partners:
EFL38184.1
Hydroxymethylglutaryl-coenzyme A reductase.
 
 
 0.997
EFL38186.1
Phosphomevalonate kinase.
 
 
 0.977
EFL43071.1
Conserved hypothetical protein.
  
 0.977
EFL38187.1
Diphosphomevalonate decarboxylase.
 
 
 0.976
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.969
EFL38188.1
Mevalonate kinase.
 
 
 0.960
EFL38395.1
Beta-ketoadipyl CoA thiolase PhaD; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.937
EFL39052.1
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.937
EFL40979.1
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.937
EFL37850.1
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.892
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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