Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL38188.1Mevalonate kinase. (367 aa)    
Predicted Functional Partners:
EFL38187.1
Diphosphomevalonate decarboxylase.
 
 
 0.996
EFL38186.1
Phosphomevalonate kinase.
 
  
 0.989
EFL38184.1
Hydroxymethylglutaryl-coenzyme A reductase.
 
 0.988
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.969
EFL38183.1
hydroxymethylglutaryl-CoA synthase.
 
 
 0.960
EFL43496.1
Polyketide TA biosynthesis protein TaC.
 
 
 0.834
EFL38189.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
 0.797
EFL39170.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
   
 
  0.789
EFL38537.1
Ferredoxin oxidoreductase, alpha subunit.
     
  0.765
EFL39776.1
Ferredoxin oxidoreductase, alpha subunit.
     
  0.765
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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