STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL38219.12-hydroxy-3-oxopropionate reductase. (296 aa)    
Predicted Functional Partners:
EFL38218.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 0.994
EFL38222.1
Glyoxylate carboligase; Belongs to the TPP enzyme family.
 
 
 0.980
EFL42765.1
6-phosphogluconate dehydrogenase, NAD-binding.
  
  
 
0.890
EFL38047.1
Glycerate kinase; Truncated CDS; Belongs to the glycerate kinase type-1 family.
  
 
 0.864
EFL39508.1
Aldehyde dehydrogenase; Overlaps another CDS with the same product name.
   
 
  0.861
EFL41288.1
Methylmalonate-semialdehyde dehydrogenase.
   
 
  0.861
EFL42204.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.861
EFL38224.1
acetyl-CoA synthetase.
  
 
  0.853
acsA
acetate-CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.853
EFL38809.1
4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.850
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.