Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL38258.1NUDIX family hydrolase; Belongs to the Nudix hydrolase family. (139 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase.
  
 
  0.785
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
    
  0.764
EFL42015.1
Endonuclease/exonuclease/phosphatase.
  
  
  0.723
EFL42248.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.706
EFL40605.1
5`-nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.698
EFL41186.1
Sugar phosphatase/hydrolase; Belongs to the HAD-like hydrolase superfamily.
    
  0.698
EFL41904.1
2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.
    
  0.698
EFL42132.1
Pyridoxal phosphate phosphatase.
    
  0.698
EFL38898.1
Hydrolase.
    
  0.686
EFL38279.1
Hypothetical protein.
    
  0.678
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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