Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL38273.1Homocysteine S-methyltransferase. (312 aa)    
Predicted Functional Partners:
EFL42595.1
Methionine-gamma lyase.
 
 
 0.922
EFL39480.1
Cystathionine gamma-synthase.
 
 
 0.918
EFL40417.1
Cys/Met metabolism PLP-dependent enzyme.
 
 
 0.918
EFL42248.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.917
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.882
EFL42770.1
Pyridoxal-phosphate dependent enzyme.
  
  
 0.880
EFL39098.1
Homoserine dehydrogenase.
   
 
 0.878
EFL40981.1
Cystathionine beta-synthase.
     
 0.857
EFL37670.1
Threonine dehydratase.
     
 0.851
EFL39476.1
Threonine dehydratase.
     
 0.851
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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