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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL38380.1Histidine kinase. (413 aa)    
Predicted Functional Partners:
EFL38381.1
Two-component system, regulatory protein.
 
  0.978
EFL38760.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
  
 0.906
EFL38759.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
  
 0.871
EFL42602.1
Response regulator, two-component system.
  
  0.825
EFL42984.1
Response regulator, two-component system.
  
  0.820
EFL39075.1
Two-component system response regulator.
  
  0.818
EFL40576.1
Two-component system response regulator.
  
  0.817
EFL37891.1
Two-component system response regulator; Truncated CDS; unextendable partial coding region.
  
  0.816
EFL39995.1
Two-component system response regulator.
  
  0.816
EFL40194.1
Two-component system response regulator.
  
  0.816
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.