Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL38387.1Conserved hypothetical protein. (224 aa)    
Predicted Functional Partners:
EFL38389.1
Ribonuclease D.
 
    0.916
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
       0.770
EFL38654.1
Conserved hypothetical protein.
  
     0.756
EFL38374.1
Chlorite O(2)-lyase.
 
     0.749
EFL41531.1
Conserved hypothetical protein.
  
     0.744
EFL41732.1
Integral membrane protein.
  
     0.744
EFL38388.1
Two-component system response regulator.
       0.721
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.714
EFL40083.1
Ser/Thr protein phosphatase.
  
     0.711
rbpA-2
Membrane-associated GTPase; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.698
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
Server load: low (16%) [HD]