Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL38431.1Integral membrane protein. (371 aa)    
Predicted Functional Partners:
EFL38430.1
Conserved hypothetical protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
       0.773
EFL38432.1
SMI1/KNR4 family protein.
       0.773
EFL41561.1
ATP/GTP-binding protein.
 
   
 0.626
EFL41563.1
Conserved hypothetical protein.
 
     0.622
EFL38428.1
Type III effector HopAN1.
       0.618
EFL38429.1
L-fuculose phosphate aldolase.
       0.618
EFL41562.1
Conserved hypothetical protein.
 
     0.509
EFL42020.1
Stress protein.
 
     0.461
EFL41559.1
Conserved hypothetical protein.
 
     0.453
EFL38427.1
3-isopropylmalate dehydrogenase.
       0.443
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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