Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL38496.12,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase. (181 aa)    
Predicted Functional Partners:
EFL39623.1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.857
EFL42655.1
Succinate-semialdehyde dehydrogenase.
  
 
 0.857
EFL38495.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.790
EFL40018.1
Benzaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.783
EFL43342.1
Phenylacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.783
EFL38494.1
Conserved hypothetical protein.
       0.780
EFL38218.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
     
  0.767
EFL43255.1
Succinate-semialdehyde dehydrogenase [NADP+] (SSDH).
  
 
 0.753
EFL38222.1
Glyoxylate carboligase; Belongs to the TPP enzyme family.
     
  0.751
EFL42910.1
Mandelate racemase/muconate lactonizing enzyme domain-containing protein.
  
 
 0.660
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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