close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL38693.1Trypsin (SET). (277 aa)    
Predicted Functional Partners:
EFL40812.1
Conserved hypothetical protein.
    
 0.905
EFL41696.1
Membrane protein.
    
 0.905
EFL38318.1
hydroxylacyl-CoA dehydrogenase.
   
 0.829
EFL38320.1
3-hydroxyacyl-CoA dehydrogenase; Unextendable partial coding region.
   
 0.829
dnaK
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.816
dnaK-2
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.816
sigA
RNA polymerase sigma (70) factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.762
EFL38992.1
Calcium-binding protein.
    
   0.753
EFL40793.1
Calcium binding protein.
    
   0.753
EFL38279.1
Hypothetical protein.
    
  0.731
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
Server load: medium (48%) [HD]