STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL39040.1Thymidylate kinase. (212 aa)    
Predicted Functional Partners:
EFL39039.1
Molybdenum cofactor biosynthesis protein A.
       0.878
EFL39041.1
ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
    
  0.822
EFL39038.1
Conserved hypothetical protein.
       0.773
tdk
Thymidine kinase.
  
 
 0.767
EFL37290.1
Thymidylate synthase.
  
 
 0.727
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.727
EFL40038.1
DNA polymerase III, delta' subunit.
  
 
 0.699
EFL37621.1
Bacterioferritin comigratory protein.
   
   0.658
EFL41153.1
Bacterioferritin comigratory protein (thioredoxin reductase).
   
   0.658
EFL41555.1
AhpC/TSA family protein.
   
   0.658
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.