Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL39374.1Leupeptin-inactivating enzyme 2. (501 aa)    
Predicted Functional Partners:
EFL39008.1
Thermolysin metallopeptidase; Extracellular zinc metalloprotease.
  
 0.917
EFL38288.1
Para-nitrobenzyl esterase; Belongs to the type-B carboxylesterase/lipase family.
  
 0.702
EFL41248.1
Agmatinase; Belongs to the arginase family.
   
 
 0.652
EFL39262.1
Thiazole biosynthesis adenylyltransferase ThiF.
   
   0.639
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.602
EFL39076.1
Chitinase 63.
  
     0.544
EFL41344.1
Serine protease; Belongs to the peptidase S8 family.
  
  
 0.511
EFL42491.1
Chitinase 63; Belongs to the glycosyl hydrolase 18 family.
  
   
 0.510
EFL41696.1
Membrane protein.
  
 
 0.504
EFL39373.1
Conserved hypothetical protein.
       0.491
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
Server load: low (10%) [HD]