Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL39502.1Dihydrolipoyl dehydrogenase. (479 aa)    
Predicted Functional Partners:
EFL39170.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
 0.995
EFL41745.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
 0.973
EFL40307.1
Pyruvate dehydrogenase E2.
 
 0.966
EFL40320.1
Pyruvate dehydrogenase E2.
 0.965
EFL40308.1
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.963
EFL40321.1
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.963
EFL37735.1
Pyruvate dehydrogenase complex, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.957
EFL41895.1
Glutamate synthase large subunit.
    
 0.921
EFL40309.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
 
 
 0.914
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.871
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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