node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFL38925.1 | EFL41895.1 | SSRG_01729 | SSRG_04699 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glutamate synthase large subunit. | 0.588 |
EFL38925.1 | EFL42114.1 | SSRG_01729 | SSRG_04918 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine phosphatase. | 0.952 |
EFL38925.1 | folD | SSRG_01729 | SSRG_02395 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.451 |
EFL38925.1 | gcvH | SSRG_01729 | SSRG_01774 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.510 |
EFL38925.1 | gcvT | SSRG_01729 | SSRG_01773 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.790 |
EFL38925.1 | glyA-3 | SSRG_01729 | SSRG_02381 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.877 |
EFL38925.1 | purH | SSRG_01729 | SSRG_02398 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.673 |
EFL38972.1 | EFL41895.1 | SSRG_01776 | SSRG_04699 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glutamate synthase large subunit. | 0.426 |
EFL38972.1 | EFL42114.1 | SSRG_01776 | SSRG_04918 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase. | 0.941 |
EFL38972.1 | gcvH | SSRG_01776 | SSRG_01774 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.798 |
EFL38972.1 | gcvT | SSRG_01776 | SSRG_01773 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.881 |
EFL38972.1 | glyA-3 | SSRG_01776 | SSRG_02381 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.884 |
EFL41895.1 | EFL38925.1 | SSRG_04699 | SSRG_01729 | Glutamate synthase large subunit. | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.588 |
EFL41895.1 | EFL38972.1 | SSRG_04699 | SSRG_01776 | Glutamate synthase large subunit. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.426 |
EFL41895.1 | folD | SSRG_04699 | SSRG_02395 | Glutamate synthase large subunit. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.681 |
EFL41895.1 | gcvH | SSRG_04699 | SSRG_01774 | Glutamate synthase large subunit. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.955 |
EFL41895.1 | gcvT | SSRG_04699 | SSRG_01773 | Glutamate synthase large subunit. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.957 |
EFL41895.1 | glyA-3 | SSRG_04699 | SSRG_02381 | Glutamate synthase large subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
EFL41895.1 | purD | SSRG_04699 | SSRG_03340 | Glutamate synthase large subunit. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.577 |
EFL41895.1 | purH | SSRG_04699 | SSRG_02398 | Glutamate synthase large subunit. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.932 |