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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)    
Predicted Functional Partners:
EFL39367.1
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.999
EFL40776.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.999
EFL41278.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.999
EFL43231.1
ferredoxin-NADP reductase.
  
 0.992
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.986
EFL42865.1
Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
  
 0.982
EFL41895.1
Glutamate synthase large subunit.
  
 
 0.966
EFL38155.1
Malate synthase A; Belongs to the malate synthase family.
   
 0.965
EFL38537.1
Ferredoxin oxidoreductase, alpha subunit.
  
 
 0.964
EFL39776.1
Ferredoxin oxidoreductase, alpha subunit.
  
 
 0.964
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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